Implicações do neoliberalismo para a educação infantil: um relato de experiência

This article is an account of experience about a Training Course exclusively for the auxiliary educational activities of Municipal Education Network (RME) of Goiânia and developed by trainees of undergraduate course (teaching degree) in Psychology, under supervision. Within a critical and transformative conception of the internship, two cards were applied, one of identification and another of evaluation, in course students. The data suggested, after analysis, that strategies to contain expenses and "downsizing" of the public machine through temporary contracting are added to the current context of serious economic and fiscal crisis, resulting in worse working conditions, loss of quality and distortion of the guidelines for Early Childhood Education in the municipality.Este artigo é um relato de experiência acerca de um Curso de Formação exclusivamente destinado às auxiliares de atividades educativas da Rede Municipal de Educação (RME) de Goiânia e desenvolvido por estagiários de Licenciatura em Psicologia, sob supervisão. Dentro de uma concepção crítica e transformadora de estágio, foram aplicadas duas fichas, uma de identificação e outra de avaliação, em alunas do curso. Os dados sugeriram, após análise, que estratégias de contenção de gastos e “enxugamento” da máquina pública através da contratação temporária se somam ao atual contexto de grave crise econômica e fiscal, resultando em piores condições de trabalho, a perda de sua qualidade e o desvirtuamento das orientações para a Educação Infantil no município

Opposing Effects of Particle Pollution, Ozone, and Ambient Temperature on Arterial Blood Pressure

Background: Diabetes increases the risk of hypertension and orthostatic hypotension and raises the risk of cardiovascular death during heat waves and high pollution episodes

Brachial Artery Responses to Ambient Pollution, Temperature, and Humidity in People with Type 2 Diabetes: A Repeated-Measures Study

Background: Extreme weather and air pollution are associated with increased cardiovascular risk in people with diabetes. Objectives: In a population with diabetes, we conducted a novel assessment of vascular brachial artery responses both to ambient pollution and to weather (temperature and water vapor pressure, a measure of humidity). Methods: Sixty-four 49- to 85-year-old Boston residents with type 2 diabetes completed up to five study visits (279 repeated measures). Brachial artery diameter (BAD) was measured by ultrasound before and after brachial artery occlusion [i.e., flow-mediated dilation (FMD)] and before and after nitroglycerin-mediated dilation (NMD). Ambient concentrations of fine particulate mass (PM2.5), black carbon (BC), organic carbon (OC), elemental carbon, particle number, and sulfate were measured at our monitoring site; ambient concentrations of carbon monoxide, nitrogen dioxide, and ozone were obtained from state monitors. Particle exposure in the home and during each trip to the clinic (home/trip exposure) was measured continuously and as a 5-day integrated sample. We used linear models with fixed effects for participants, adjusting for date, season, temperature, and water vapor pressure on the day of each visit, to estimate associations between our outcomes and interquartile range increases in exposure. Results: Baseline BAD was negatively associated with particle pollution, including home/trip–integrated BC (–0.02 mm; 95% CI: –0.04, –0.003, for a 0.28 μg/m3 increase in BC), OC (–0.08 mm; 95% CI: –0.14, –0.03, for a 1.61 μg/m3 increase) as well as PM2.5, 5-day average ambient PM2.5, and BC. BAD was positively associated with ambient temperature and water vapor pressure. However, exposures were not consistently associated with FMD or NMD. Conclusion: Brachial artery diameter, a predictor of cardiovascular risk, decreased in association with particle pollution and increased in association with ambient temperature in our study population of adults with type 2 diabetes. Citation: Zanobetti A, Luttmann-Gibson H, Horton ES, Cohen A, Coull BA, Hoffmann B, Schwartz JD, Mittleman MA, Li Y, Stone PH, de Souza C, Lamparello B, Koutrakis P, Gold DR. 2014. Brachial artery responses to ambient pollution, temperature, and humidity in people with type 2 diabetes: a repeated-measures study. Environ Health Perspect 122:242–248; http://dx.doi.org/10.1289/ehp.120613

Antioxidant, antimicrobial and immunostimulant properties of saline extract from Caesalpinia pulcherrima (L.) Swartz (Fabaceae) leaves

281-289Caesalpinia pulcherrima (L.) Swartz is a species that originates in India and Central America and is widely distributed in the world. This plant presents important biological properties, due to the presence of some secondary medicinal metabolites, such as tannins, glycosides, flavonoids and diterpenes. In folk medicine, C. pulcherrima is used in different diseases as bronchitis, asthma, infections, wounds and eye irritations. The aim of this study was to perform a phytochemical screening and evaluate which biological properties the saline extract of leaves from C. pulcherrima have against microorganisms and animal cells. Results showed that 15 majority compounds could be found in saline extract distributed among phenol, coumarin and quercetin groups.Saline extract of leaves from C. pulcherrima also showed good results in antioxidant test and showed significant antifungal property against Candida strains. Moreover, the saline extract did not showed cytotoxicity against mice splenocytes and promoted proliferation in these cells. These results may be predictive for future studies using the saline extract from C. pulcherrima leaves as cell stimulant agent in a pharmaceutical phytotherapic formulation used in cicatricial and in vitro immunostimulant assays

Isolation of circulating tumor cells from glioblastoma patients by direct immunomagnetic targeting

Glioblastoma (GBM) is the most common form of primary brain cancer in adults and tissue biopsies for diagnostic purposes are often inaccessible. The postulated idea that brain cancer cells cannot pass the blood-brain barrier to form circulating tumor cells (CTCs) has recently been overthrown and CTCs have been detected in the blood of GBM patients albeit in low numbers. Given the potential of CTCs to be analyzed for GBM biomarkers that may guide therapy decisions it is important to define methods to better isolate these cells. Here, we determined markers for immunomagnetic targeting and isolation of GBM-CTCs and confirmed their utility for CTC isolation from GBM patient blood samples. Further, we identified a new marker to distinguish isolated GBM-CTCs from residual lymphocytes

Isolation of circulating tumor cells from glioblastoma patients by direct immunomagnetic targeting

Glioblastoma (GBM) is the most common form of primary brain cancer in adults and tissue biopsies for diagnostic purposes are often inaccessible. The postulated idea that brain cancer cells cannot pass the blood-brain barrier to form circulating tumor cells (CTCs) has recently been overthrown and CTCs have been detected in the blood of GBM patients albeit in low numbers. Given the potential of CTCs to be analyzed for GBM biomarkers that may guide therapy decisions it is important to define methods to better isolate these cells. Here, we determined markers for immunomagnetic targeting and isolation of GBM-CTCs and confirmed their utility for CTC isolation from GBM patient blood samples. Further, we identified a new marker to distinguish isolated GBM-CTCs from residual lymphocytes

Sexualidade, Diálogo e Extensão Universitária: Ações em Promoção à Saúde

É no contexto da adolescência em que surgem questionamentos e dúvidas quanto à vivência da sexualidade as quais devem ser esclarecidas por meio do âmbito familiar, escolar, social e cultural, pois são importantes ao desenvolvimento desses indivíduos. Sendo assim, mesmo diante de tabus e preconceitos, discussões acerca dessa temática são imprescindíveis, pois implica em ações sobre o cuidado e promoção da saúde. O presente estudo foi realizado em uma Escola Estadual e na Universidade Federal, ambas localizadas no município de Maceió-AL, tendo caráter quali-quantitativo. No âmbito escolar, avaliou-se os adolescentes do ensino médio acerca das principais fontes de informações, influências e conhecimentos sobre ISTs. Os participantes do gênero masculino mostraram menos saberes que os do gênero feminino em relação à temática e ambos apresentaram deficientes conhecimentos sobre ISTs. No âmbito universitário, foi avaliado se os cursos de graduação em Serviço Social, Pedagogia, Psicologia e Biologia Licenciatura abordam a temática sexualidade e se os futuros profissionais se sentem preparados para abordar o tema na carreira. Os resultados mostram a necessidade de formação profissional complementar. Assim, é notório a necessidade de intervenções educativas para que os indivíduos possam viver sua sexualidade de modo pleno e saudável

The discovery space of ELT-ANDES. Stars and stellar populations

The ArmazoNes high Dispersion Echelle Spectrograph (ANDES) is the optical and near-infrared high-resolution echelle spectrograph envisioned for the European Extremely Large Telescope (ELT). We present a selection of science cases, supported by new calculations and simulations, where ANDES could enable major advances in the fields of stars and stellar populations. We focus on three key areas, including the physics of stellar atmospheres, structure, and evolution; stars of the Milky Way, Local Group, and beyond; and the star-planet connection. The key features of ANDES are its wide wavelength coverage at high spectral resolution and its access to the large collecting area of the ELT. These features position ANDES to address the most compelling and potentially transformative science questions in stellar astrophysics of the decades ahead, including questions which cannot be anticipated today.Comment: 46 pages, 8 figures; submitted to Experimental Astronomy on behalf of the ANDES Science Tea